.asem-guidelines{--gg-navy:#102955;--gg-blue:#11428b;--gg-purple:#5e22bc;--gg-border:#d8e6fb;--gg-muted:#425879;color:var(--gg-navy);font-family:Roboto,Arial,sans-serif;background:#fff}
.asem-guidelines,.asem-guidelines *{box-sizing:border-box}
.asem-guidelines :where(section){padding:0}
.asem-guidelines a{color:inherit;text-decoration:none}
.asem-guidelines a:focus-visible,.asem-guidelines button:focus-visible,.asem-guidelines select:focus-visible,.asem-guidelines input:focus-visible{outline:3px solid #792ee7;outline-offset:3px}
.asem-guidelines-wrap{width:min(100% - 56px,1380px);margin-inline:auto}
.asem-guidelines h1,.asem-guidelines h2,.asem-guidelines h3,.asem-guidelines p{margin-top:0}
.asem-guidelines h1,.asem-guidelines h2,.asem-guidelines h3{font-family:Lexend,Arial,sans-serif;color:var(--gg-navy)}
.asem-guidelines-hero{min-height:228px;background:linear-gradient(100deg,#fff 0%,#eff6ff 49%,#dbeafa 100%);overflow:hidden}
.asem-guidelines-hero__inner{position:relative;min-height:228px;display:flex;align-items:center}
.asem-guidelines-hero__copy{position:relative;z-index:2;width:min(64%,730px);padding:21px 0 17px 18px}
.asem-guidelines-eyebrow{margin:0 0 4px;color:#502199;font:700 12px/1.4 Lexend,Arial,sans-serif;letter-spacing:.025em;text-transform:uppercase}
.asem-guidelines-hero h1{font-size:clamp(25px,2.15vw,34px);line-height:1.18;letter-spacing:-.035em;margin:0 0 4px;font-weight:700}
.asem-guidelines-hero__intro{font-size:15px;line-height:1.42;max-width:590px;color:#294064;margin:0 0 15px}
.asem-guidelines-search{height:43px;width:min(100%,705px);display:flex;align-items:center;background:#fff;border:1px solid #cddff6;border-radius:6px;box-shadow:0 4px 16px rgba(34,75,138,.06);padding:3px 3px 3px 13px}
.asem-guidelines-search>i{color:#254d98;font-size:16px;margin-right:10px}
.asem-guidelines-search input{min-width:0;flex:1;height:100%;border:0;background:transparent;color:var(--gg-navy);font-size:14px;outline:0}
.asem-guidelines-search input::placeholder{color:#5d708e;opacity:1}
.asem-guidelines-search button{border:0;border-radius:4px;background:#5a21b5;color:#fff;height:35px;min-width:102px;padding:0 15px;font-weight:700;font-size:13px;cursor:pointer}
.asem-guidelines-search button:hover{background:#43138f}
.asem-guidelines-chips{display:flex;gap:7px;align-items:center;width:min(850px,calc(100vw - 94px));overflow-x:auto;scrollbar-width:thin;padding-top:12px;white-space:nowrap}
.asem-guidelines-chips a{font-size:11px;font-weight:700;color:#173866;background:#f8fbff;border:1px solid #b9d3fb;border-radius:20px;padding:6px 11px;line-height:1.2;white-space:nowrap}
.asem-guidelines-chips a:hover,.asem-guidelines-chips a[aria-current]{border-color:#5f30c8;color:#5f25b8;background:#f5efff}
.asem-guidelines-chips__all{background:#fff!important;border-color:#dce6f6!important}
.asem-guidelines-chips__all i{margin-left:5px}
.asem-guidelines-hero__art{position:absolute;inset:0 -28px 0 auto;width:43%;background:url('../images/guidelines/hero-clinical-reference-v1.webp') center right/cover no-repeat}
.asem-guidelines-hero__art:before{content:"";position:absolute;inset:0;background:linear-gradient(90deg,#e9f4ff 0%,rgba(237,246,255,.22) 38%,rgba(214,232,250,.05) 100%)}
.asem-guidelines-hero__callout{position:absolute;top:28px;left:14%;z-index:1;width:210px;min-height:148px;padding:15px 15px 13px 18px;background:rgba(240,247,255,.76);backdrop-filter:blur(3px);border-radius:8px;color:var(--gg-navy);font-size:15px;line-height:1.28}
.asem-guidelines-hero__callout i{display:block;font-size:27px;color:var(--gg-purple);margin-bottom:9px}
.asem-guidelines-hero__callout b{display:block;width:25px;height:2px;background:var(--gg-purple);margin-top:10px}
.asem-guidelines-body{padding-top:17px;padding-bottom:26px}
.asem-guidelines-section-heading{display:flex;align-items:center;gap:12px;margin-bottom:9px}
.asem-guidelines-section-heading h2{font-size:16px;line-height:1.3;margin:0;font-weight:700;white-space:nowrap}
.asem-guidelines-section-heading>span{width:39px;height:2px;background:#7e39ee}
.asem-guidelines-section-heading>a{font-size:11px;color:#4b159c;font-weight:700;margin-left:auto}
.asem-guidelines-section-heading>a i{margin-left:5px}
.asem-guidelines-featured__grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:11px}
.asem-guidelines-feature-card{min-width:0;min-height:164px;display:flex;gap:13px;padding:10px;border:1px solid var(--gg-border);border-radius:7px;background:#fff;box-shadow:0 2px 12px rgba(27,70,138,.025)}
.asem-guidelines-feature-card__visual{width:98px;flex:0 0 98px;height:105px;overflow:hidden;border-radius:6px;background:#edf4ff}
.asem-guidelines-feature-card__visual img{width:100%;height:100%;object-fit:cover}
.asem-guidelines-feature-card__body{min-width:0;flex:1;display:flex;flex-direction:column}
.asem-guidelines-badge{align-self:flex-start;border-radius:5px;padding:4px 7px;background:#f2e7ff;color:#6424ae;font-size:10px;font-weight:700;text-transform:uppercase;line-height:1.1}
.asem-guidelines-feature-card h3{font-size:14px;line-height:1.25;margin:6px 0 4px;font-weight:700;display:-webkit-box;-webkit-line-clamp:2;-webkit-box-orient:vertical;overflow:hidden}
.asem-guidelines-feature-card h3 a:hover,.asem-guidelines-row h3 a:hover{color:#5720b4}
.asem-guidelines-feature-card p{font-size:11px;color:#3e5172;line-height:1.25;margin:0 0 5px;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}
.asem-guidelines-feature-card small{font-size:11px;color:#29466e;line-height:1.25}
.asem-guidelines-feature-card__bottom{display:flex;gap:6px;align-items:end;justify-content:space-between;margin-top:auto;padding-top:7px}
.asem-guidelines-status{display:inline-block;align-self:flex-start;background:#d8f8f2;border-radius:20px;padding:4px 9px;color:#087d79;font-size:10px;font-weight:700;line-height:1.2;white-space:nowrap}
.asem-guidelines-feature-card__bottom a{font-size:11px;font-weight:700;color:#551bae;white-space:nowrap}
.asem-guidelines-feature-card__bottom a i{margin-left:3px}
.asem-guidelines-filter-section{margin-top:18px}
.asem-guidelines-filter-form{display:grid;grid-template-columns:repeat(6,minmax(0,1fr)) auto;gap:7px;align-items:end}
.asem-guidelines-filter-form label{min-width:0;min-height:48px;border:1px solid var(--gg-border);border-radius:6px;background:#fff;padding:4px 10px;display:flex;flex-direction:column;justify-content:center}
.asem-guidelines-filter-form label span{font-size:10px;color:#547096;line-height:1.2}
.asem-guidelines-filter-form select{width:100%;appearance:auto;border:0;background:transparent;color:#163867;font-size:13px;font-weight:600;padding:0;min-height:22px;text-overflow:ellipsis}
.asem-guidelines-filter-form .nice-select{float:none;width:100%;height:24px;line-height:24px;min-height:0;margin:0;padding:0 20px 0 0;border:0;box-shadow:none;background:transparent;color:#163867;font-size:13px;font-weight:600}
.asem-guidelines-filter-form .nice-select .list{max-height:290px;overflow-y:auto;z-index:20}
.asem-guidelines-filter-form__apply{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap}
.asem-guidelines-filter-form__reset{font-size:12px;font-weight:700;color:#1748a8!important;white-space:nowrap;align-self:center;padding-left:12px}
.asem-guidelines-filter-form__reset i{margin-right:5px}
.asem-guidelines-content-grid{display:grid;grid-template-columns:minmax(0,2.15fr) minmax(275px,.95fr);gap:30px;margin-top:19px;align-items:start;scroll-margin-top:94px}
.asem-guidelines-list{min-width:0}
.asem-guidelines-list__head{display:flex;align-items:center;justify-content:space-between;gap:10px;min-height:27px;margin-bottom:7px}
.asem-guidelines-list__head h2{font-size:15px;line-height:1.25;font-weight:700;margin:0}
.asem-guidelines-list__head h2 small{font:400 12px/1.25 Roboto,Arial,sans-serif;color:#526989}
.asem-guidelines-list__head label,.asem-guidelines-per-page label{font-size:11px;color:#526989;display:flex;align-items:center;gap:5px;white-space:nowrap}
.asem-guidelines-list__head select,.asem-guidelines-per-page select{border:1px solid var(--gg-border);border-radius:5px;background:#fff;color:#17335d;font-size:11px;font-weight:600;height:29px;padding:0 5px;max-width:110px}
.asem-guidelines-list__head .nice-select,.asem-guidelines-per-page .nice-select{float:none;height:29px;line-height:27px;min-height:0;margin:0;padding:0 22px 0 7px;border:1px solid var(--gg-border);border-radius:5px;background:#fff;color:#17335d;font-size:11px;font-weight:600}
.asem-guidelines-row{min-width:0;display:grid;grid-template-columns:52px 78px minmax(0,1fr) 138px;gap:9px;align-items:center;min-height:83px;border:1px solid var(--gg-border);border-radius:6px;background:#fff;padding:7px 9px;margin-bottom:7px}
.asem-guidelines-row__date{display:flex;flex-direction:column;justify-content:center;align-items:center;width:52px;height:62px;border-radius:5px;background:#edf5ff;color:#163967;font-size:10px;line-height:1.3;text-align:center}
.asem-guidelines-row__date strong{font-size:15px;font-weight:800}
.asem-guidelines-row__visual{width:78px;height:69px;overflow:hidden;border-radius:5px;background:#e8f2ff}
.asem-guidelines-row__visual img{width:100%;height:100%;object-fit:cover}
.asem-guidelines-row__copy{min-width:0}
.asem-guidelines-row__tags{display:flex;flex-wrap:wrap;gap:5px;margin-bottom:4px}
.asem-guidelines-row__tags span{font-size:9px;line-height:1.25;color:#0a4b99;background:#e8f4ff;border-radius:4px;padding:3px 5px;text-transform:uppercase;font-weight:700}
.asem-guidelines-row__tags span+span{color:#255380;background:#eff5fc}
.asem-guidelines-row h3{font-size:13px;line-height:1.24;margin:0 0 3px;font-weight:700;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.asem-guidelines-row__copy p{font-size:11px;line-height:1.25;color:#334969;margin:0 0 2px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.asem-guidelines-row__copy small{display:block;font-size:10px;line-height:1.25;color:#526989;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
.asem-guidelines-row__actions{display:flex;flex-direction:column;align-items:stretch;gap:4px}
.asem-guidelines-row__actions .asem-guidelines-status{align-self:flex-end;margin-bottom:2px}
.asem-guidelines-row__actions a{display:flex;justify-content:space-between;align-items:center;gap:4px;border:1px solid #b9d3fa;border-radius:4px;padding:5px 6px;color:#1450a1;font-size:10px;font-weight:700;line-height:1.15;white-space:nowrap}
.asem-guidelines-row__actions a:hover{background:#edf5ff}
.asem-guidelines-empty{border:1px solid var(--gg-border);border-radius:7px;padding:28px;font-size:15px;color:var(--gg-muted);line-height:1.5}
.asem-guidelines-empty a{color:#4c1a9d;text-decoration:underline}
.asem-guidelines-pagination{display:flex;justify-content:center;margin-top:17px}
.asem-guidelines-pagination .pagination{gap:6px;flex-wrap:wrap}
.asem-guidelines-pagination .page-link{border:1px solid #c9dbf4;border-radius:5px!important;color:#234980;font-size:12px;min-width:29px;text-align:center;padding:5px 7px}
.asem-guidelines-pagination .active .page-link{background:#5d21b7;border-color:#5d21b7;color:#fff}
.asem-guidelines-per-page{display:flex;justify-content:flex-end;margin-top:7px}
.asem-guidelines-sidebar{display:grid;gap:16px}
.asem-guidelines-panel{border:1px solid var(--gg-border);border-radius:6px;padding:12px;background:#fff}
.asem-guidelines-panel h2{font-size:15px;line-height:1.25;margin:0 0 10px;border-left:3px solid #7226cf;padding-left:7px}
.asem-guidelines-stats{display:grid;grid-template-columns:1fr 1fr;gap:14px 10px}
.asem-guidelines-stats>div{display:grid;grid-template-columns:40px minmax(0,1fr);grid-template-rows:auto auto;column-gap:8px;align-items:center;min-width:0}
.asem-guidelines-stats i{grid-row:1/3;display:grid;place-items:center;width:36px;height:36px;border-radius:6px;background:#f0eaff;color:#6927c7;font-size:18px}
.asem-guidelines-stats>div:nth-child(2) i{background:#e9f3ff;color:#1b68d9}
.asem-guidelines-stats>div:nth-child(4) i{background:#e5faf8;color:#0b9f9a}
.asem-guidelines-stats strong{font-size:16px;line-height:1.1;color:#123469}
.asem-guidelines-stats span{font-size:10px;line-height:1.2;color:#415978}
.asem-guidelines-side-list{list-style:none;margin:0;padding:0;display:grid;gap:7px}
.asem-guidelines-side-list li{display:flex;align-items:center;gap:8px;min-width:0}
.asem-guidelines-side-list time{width:40px;min-width:40px;height:38px;border-radius:5px;background:#edf5ff;display:flex;align-items:center;justify-content:center;flex-direction:column;font-size:10px;color:#173966;line-height:1.1}
.asem-guidelines-side-list time strong{font-size:13px}
.asem-guidelines-side-list li>div{min-width:0}
.asem-guidelines-side-list a{display:block;font-size:11px;font-weight:700;line-height:1.25;color:#143664;display:-webkit-box;-webkit-line-clamp:2;-webkit-box-orient:vertical;overflow:hidden}
.asem-guidelines-side-list a:hover{color:#6527bc}
.asem-guidelines-side-list small{display:block;font-size:10px;color:#526989;line-height:1.3;margin-top:2px}
.asem-guidelines-detail{padding:27px 0 70px;background:#f7faff;min-height:65vh}
.asem-guidelines-detail__breadcrumb{display:flex;gap:9px;color:#455f83;font-size:13px;margin-bottom:24px}
.asem-guidelines-detail__breadcrumb a:hover{text-decoration:underline}
.asem-guidelines-detail__hero{background:linear-gradient(105deg,#fff,#eaf3ff);border:1px solid var(--gg-border);border-radius:12px;padding:32px;margin-bottom:20px}
.asem-guidelines-detail__hero h1{font-size:clamp(25px,2.6vw,40px);line-height:1.2;max-width:900px;margin:0 0 18px}
.asem-guidelines-detail__meta{display:flex;flex-wrap:wrap;align-items:center;gap:9px;font-size:13px;color:#3e5879}
.asem-guidelines-detail__meta>span:not(:last-child){border-right:1px solid #bcd0e7;padding-right:9px}
.asem-guidelines-detail__grid{display:grid;grid-template-columns:minmax(0,2fr) minmax(260px,1fr);gap:20px}
.asem-guidelines-detail__main,.asem-guidelines-detail__facts{background:#fff;border:1px solid var(--gg-border);border-radius:10px;padding:26px}
.asem-guidelines-detail__main h2,.asem-guidelines-detail__facts h2,.asem-guidelines-detail__related h2{font-size:21px;margin:0 0 15px}
.asem-guidelines-detail__main p{font-size:16px;line-height:1.65;color:#304869;max-width:760px}
.asem-guidelines-detail__notice{background:#eef6ff;border-left:3px solid #4a89d5;padding:10px 14px;font-size:14px!important}
.asem-guidelines-detail__primary{display:inline-flex;align-items:center;gap:15px;background:#5b22b7;color:#fff!important;padding:12px 18px;border-radius:6px;font-weight:700;font-size:14px}
.asem-guidelines-detail__primary:hover{background:#42158d}
.asem-guidelines-detail__facts dl{margin:0 0 20px}
.asem-guidelines-detail__facts dl>div{padding:8px 0;border-bottom:1px solid #e3edf8}
.asem-guidelines-detail__facts dt{font-size:12px;color:#60718b;font-weight:400}
.asem-guidelines-detail__facts dd{font-size:14px;color:#173963;margin:2px 0 0;font-weight:700}
.asem-guidelines-detail__facts>a{color:#4b1aa3;font-weight:700;font-size:13px;overflow-wrap:anywhere}
.asem-guidelines-detail__related{margin-top:28px}
.asem-guidelines-detail__related>div{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px}
.asem-guidelines-detail__related a{border:1px solid var(--gg-border);border-radius:7px;background:#fff;padding:15px;color:#173966;font-size:14px;font-weight:700}
.asem-guidelines-detail__related a i{color:#5d24b5;margin-left:5px}
@media(max-width:1100px){.asem-guidelines-featured__grid{grid-template-columns:repeat(2,minmax(0,1fr))}.asem-guidelines-feature-card:nth-child(3){display:none}.asem-guidelines-filter-form{grid-template-columns:repeat(3,minmax(0,1fr)) auto}.asem-guidelines-filter-form__reset{grid-column:4;grid-row:1/3}.asem-guidelines-content-grid{grid-template-columns:minmax(0,1.8fr) minmax(235px,.9fr);gap:18px}.asem-guidelines-row{grid-template-columns:46px 64px minmax(0,1fr)}.asem-guidelines-row__actions{grid-column:3;flex-direction:row;flex-wrap:wrap;align-items:center}.asem-guidelines-row__actions .asem-guidelines-status{margin:0 4px 0 0}.asem-guidelines-row__visual{width:64px;height:64px}}
@media(max-width:767px){.asem-guidelines-wrap{width:min(100% - 32px,560px)}.asem-guidelines-hero,.asem-guidelines-hero__inner{min-height:0}.asem-guidelines-hero__copy{width:100%;padding:28px 0 22px}.asem-guidelines-hero h1{font-size:28px;max-width:370px}.asem-guidelines-hero__intro{font-size:15px;max-width:390px}.asem-guidelines-hero__art{opacity:.2;inset:0 0 0 auto;width:58%;background-position:center}.asem-guidelines-hero__callout{display:none}.asem-guidelines-chips{width:auto;margin-right:-16px;padding-bottom:3px}.asem-guidelines-featured__grid{grid-template-columns:1fr}.asem-guidelines-feature-card:nth-child(3){display:flex}.asem-guidelines-feature-card{min-height:135px}.asem-guidelines-feature-card__visual{height:100px}.asem-guidelines-filter-form{grid-template-columns:repeat(2,minmax(0,1fr));gap:7px}.asem-guidelines-filter-form__reset{grid-column:auto;grid-row:auto;padding-left:4px}.asem-guidelines-content-grid{grid-template-columns:1fr;gap:25px}.asem-guidelines-sidebar{grid-template-columns:1fr 1fr}.asem-guidelines-panel:first-child{grid-column:1/-1}.asem-guidelines-row{grid-template-columns:44px 61px minmax(0,1fr);gap:7px;padding:7px}.asem-guidelines-row__date{width:44px;height:55px}.asem-guidelines-row__date strong{font-size:13px}.asem-guidelines-row__visual{width:61px;height:61px}.asem-guidelines-row__copy h3{white-space:normal;display:-webkit-box;-webkit-line-clamp:2;-webkit-box-orient:vertical;font-size:12px}.asem-guidelines-row__copy small{display:none}.asem-guidelines-row__actions{grid-column:1/-1;justify-content:flex-end}.asem-guidelines-row__actions a{font-size:10px}.asem-guidelines-detail__grid{grid-template-columns:1fr}.asem-guidelines-detail__related>div{grid-template-columns:1fr}.asem-guidelines-detail__hero{padding:22px}.asem-guidelines-detail__main,.asem-guidelines-detail__facts{padding:20px}}
@media(max-width:450px){.asem-guidelines-hero h1{font-size:25px}.asem-guidelines-search input{font-size:14px}.asem-guidelines-search button{min-width:82px;padding:0 8px;font-size:12px}.asem-guidelines-sidebar{grid-template-columns:1fr}.asem-guidelines-list__head{align-items:flex-start}.asem-guidelines-list__head h2{max-width:180px}.asem-guidelines-list__head h2 small{display:block}.asem-guidelines-feature-card__visual{width:82px;flex-basis:82px}.asem-guidelines-feature-card h3{font-size:13px}.asem-guidelines-feature-card__bottom{flex-wrap:wrap}.asem-guidelines-feature-card__bottom a{font-size:11px}.asem-guidelines-row h3{font-size:13px}.asem-guidelines-row__copy p{font-size:12px}.asem-guidelines-row__tags span{font-size:10px}.asem-guidelines-row__actions a{font-size:11px;min-height:32px;padding:6px 8px}.asem-guidelines-row__actions .asem-guidelines-status{margin-right:auto}}
@media(max-width:450px){.asem-guidelines-section-heading{flex-wrap:wrap}.asem-guidelines-section-heading>a{flex-basis:100%;margin-left:0;text-align:right;font-size:12px}.asem-guidelines-feature-card__visual{width:72px;flex-basis:72px}}